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Referenties
1. Schade DS, Eaton RP. Metabolic and clinical signicance of ketosis. Special Topics in
Endocrinology and Metabolism 1982; 4:1–27.
2. Wiggam MI, O’Kane MJ, Harper R, Atkinson AB, Hadden DR, Trimble ER, Bell PM. Treatment of
diabetic ketoacidosis using normalization of blood 3-hydroxybutyrate concentration as the
endpoint of emergency management. Diabetes Care 1997; 20:1347–1352.
3. Harano Y, Kosugi K, Hyosu T, Suzuki M, Hidaka H, Kashiwagi A, Uno S, Shigeta Y. Ketone bodies as
markers for Type 1 (insulin-dependent) diabetes and their value in the monitoring of diabetes
control. Diabetologia 1984; 26:343-348.
4. Ubukata E. Diurnal variation of blood ketone bodies in insulin-dependent diabetes mellitus
and non-insulin-dependent diabetes mellitus patients: The relationship to serum C-peptide
immunoreactivity and free insulin. Ann Nutr Metab 1990; 34:333–342.
5. Luzi L, Barrett EJ, Groop LC, Ferrannini E, DeFronzo RA. Metabolic eects of low-dose insulin
therapy on glucose metabolism in diabetic ketoacidosis. Diabetes 1988; 37:1470–1477.
6. Hale PJ, Crase J, Nattrass M. Metabolic eects of bicarbonate in the treatment of diabetic
ketoacidosis. Br Med J 1984; 289; 1035–1038.
7. Directive 1999/45/EC of the European Parliament and of the Council of 31 May 1999 concerning
the approximation of the laws, regulations and administrative provisions of the Member States
relating to the classication, packaging and labelling of dangerous preparations.
ART20312_Rev-B-Guide.indd 45 7/6/11 9:25 AM
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